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Tuesday, July 28, 2020 | History

3 edition of Cell biology of breast cancer found in the catalog.

Cell biology of breast cancer

Cell biology of breast cancer

  • 249 Want to read
  • 38 Currently reading

Published by Academic Press in New York .
Written in English

    Subjects:
  • Breast -- Cancer -- Congresses.,
  • Cancer cells -- Congresses.,
  • Breast neoplasms -- Physiopathology -- Congresses.,
  • Cell transformation, Neoplastic -- Congresses.,
  • Research -- Congresses.,
  • Epithelium -- Cytology -- Congresses.

  • Edition Notes

    Statementedited by Charles McGrath, Michael J. Brennan and Marvin A. Rich.
    ContributionsMcGrath, Charles M., Brennan, Michael James., Rich, Marvin A., Michigan Cancer Foundation.
    Classifications
    LC ClassificationsRC280.B8 C44
    The Physical Object
    Paginationxv, 516 p. :
    Number of Pages516
    ID Numbers
    Open LibraryOL4099429M
    ISBN 100124839401
    LC Control Number80013804

      Carey, L. A. et al. Race, breast cancer subtypes, and survival in the carolina breast cancer study. JAMA , (). CAS Article Google Scholar. Single-cell sequencing of cells isolated from bone marrow aspirates of patients with localized breast cancer, in parallel with intratumor genetic heterogeneity profiling of the bulk tumor DNA, is a powerful approach for the identification of genuine DTCs and the subsequent study of their biology .

    Cancer Cell Metabolism. Research in cancer cell metabolism focuses on altered cellular metabolism that supports the cancer phenotype characterized by unchecked cellular proliferation, resistance to metabolic and oxidative stress, ability to evade programmed cell death, reduced dependence on growth factor signals, insensitivity to growth inhibitory signals, and resistance to therapeutic. Approximately 30% of breast cancer risk is inherited, yet the majority of genetic risk factors remain unknown. Of the known genetic risks, most are thought to directly affect the malignant cancer cell and have been linked to aggressive disease, reduced response to chemotherapy, shorter times between relapse and shorter survival.

    This book offers a comprehensive overview of recent developments in the field of breast cancer biology. It is a complete and descriptive reference on motioning pathways and new treatment options for the future transnational scientists and clinicians working on cancer research and treatment. We greatly appreciate the work of all the contributors to this book. They have brought with them Author: Dil Afroze, Bilal Rah, Shazia Ali, Faheem Shehjar, Mohd Ishaq Dar, Shailender S. Chauhan, Natasha Th. 13 hours ago  Triple-negative breast cancer (TNBC), characterized by the absence or low expression of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor (HER2), is the most aggressive subtype of breast cancer. TNBC accounts for about 15% of breast cancer cases in the U.S., and is known for high relapse rates and poor overall survival (OS).


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Cell biology of breast cancer Download PDF EPUB FB2

Highlighting recent advances in our understanding of breast cancer, this book is intended for a wide audience as a reference book. Included are reviews of genetics, epigenetics, various aspects of cell and molecular biology, and several other areas of breast cancer that are aimed at determining new intervention sites for treatments and cures of the disease.

Recent studies suggest that breast cancer cells under estrogen control can synthesize and secrete their own growth factors that could autostimulate breast cancer cells or adjacent stromal tissues through autocrine or paracrine mechanisms. Stromal tissues may also secrete growth factors, such as IGF-1 and IGF-2, that can stimulate breast cancer by: 5.

27 rows  Breast Cancer - From Biology to Medicine thoroughly examines breast cancer from basic Author: Phuc Van Pham.

Cell Biology of Cancer. The cell is the fundamental unit of life. It is the smallest structure of the body capable of performing all of the processes that define life. Each of the organs in the body, such as the lung, breast, colon, and brain, consists of specialized cells that carry out the organ's functions such as the transportation of oxygen, digestion of nutrients, excretion of waste.

The recognition that the cancer cell is in a symbiotic relationship with the tumor microenvironment has created opportunities to study the interactions of cancer cells within the tumor or the host microenvironment. Researchers are now studying the molecular mechanisms and signaling pathways of cancer cell development, proliferation, and metastasis.

Cancer Genetics demonstrates how cancer cells differ from normal cells in structure and function. It examines specific cancer-related genes, such as oncogenes and tumor suppressor genes, and discusses inherited syndromes that are associated with cancer, including certain forms of breast cancer.

Ilina et al. investigate the balance between cell adhesion and matrix density on patterns of collective breast cancer cell invasion using three-dimensional models of the extracellular matrix, in.

Breast cancer is one of the most common cancer types. Due to the complexity of this disease, it is important to face its study with an integrated and multilevel approach, from genes, transcripts and proteins to molecular networks, cell populations and tissues.

According to the systems biology perspective, the biological functions arise from complex networks: in this context, concepts like. However, upon paclitaxel triggering apoptosis, rhPDCD5 protein potentiated chemotherapeutic drugs-induced growth arrest in MDA-MB, SK-BR-3, and ZR breast cancer cells.

In vivo, we use a human breast cancer xenograft model to study. We found that rhPDCD5 dramatically improves the antitumor effects of paclitaxel treatment by. Depending on the combination of cell receptor molecules present on the surface of the cancer cells, breast cancer is classified into one of three types: Luminal A, Luminal B and HER2+.

Collection: Cancer Biology We have assembled a collection of recent papers that highlights the many facets of cancer biology, including a mix of cancer subtypes and approaches. The papers cover topics ranging from the initiation of tumor formation to cancer progression and metastasis, as well as therapeutic approaches.

Author: Marc E. Lippman Publisher: Springer Science & Business Media ISBN: Size: MB Format: PDF, Kindle Category: Medical Languages: en Pages: View: Get Books Book Description: Breast Cancer Cellular And Molecular Biology by Marc E.

Lippman, Breast Cancer Cellular And Molecular Biology Book available in PDF, EPUB, Mobi Format. This book compiles the latest research and key findings about the role of circulating tumor cells (CTCs) in Breast Cancer progression, both from the research and clinical standpoint.

Based on latest advancements, the content of the book is set out to provide a clear overview about the biology and use of CTCs as a tool for the monitoring and.

New Therapies May Emerge From Our Knowledge of Cancer Biology. Our growing understanding of cancer cell biology and tumor progression is gradually leading to better methods for treating the disease, and not only by targeting defects in cell cycle arrest and DNA repair processes.

As an example, estrogen antagonists (such as tamoxifen) and drugs. Introduction to Cancer Biology 11 How cancer arises Figure Percentage of cancers attributed to excessive alcohol consumption and tobacco use. Excessive alcohol use has been linked to liver and mouth/throat cancers in both males and females.

Breast cancer risk is. A malignant tumor can invade surrounding tissue and destroy it. Cancer cells also can break away from a malignant tumor and enter the bloodstream or lymphatic system. This is how cancer spreads within the body. When breast cancer spreads outside the breast, cancer cells.

Structured in seven sections, the book starts with a review of the development and biology of multicellular organisms, how they maintain a healthy homeostasis in an individual, and a description of the molecular basis of cancer development.

The book then illustrates how, once cells become neoplastic, their signalling network is altered and. Download Cellular And Molecular Biology Of Mammary Cancer books, The idea for this book arose during the Gordon Conference on "Mammary Gland Biology".

New developments in the methodology of cell biology and the explosive growth of molecular biology had begun to impact upon our understanding of mammary gland growth and function.

COVID Resources. Reliable information about the coronavirus (COVID) is available from the World Health Organization (current situation, international travel).Numerous and frequently-updated resource results are available from this ’s WebJunction has pulled together information and resources to assist library staff as they consider how to handle coronavirus.

Hokkaido University scientists have shown that Interleukin is a prognostic marker and drug target for Triple Negative Breast Cancer. Readers are informed about the detailed molecular biology of the disease, including an elaborate exploration of altered cellular metabolism in breast cancer.

The book represents a .The Biology of Cancer is a textbook for undergraduate and graduate biology students as well as medical students studying the molecular and cellular bases of cancer. The book presents the principles of cancer biology in an organized, cogent, and in-depth manner.

The clarity of writing and the lucid full-color art program make the book accessible and engaging.5/5(1).Highlighting recent advances in our understanding of breast cancer, this book is intended for a wide audience as a reference book.

Included are reviews of genetics, epigenetics, various aspects of cell and molecular biology, and several other areas of breast cancer that are aimed at determining new intervention sites for treatments and cures of the : Heide Schatten.